HEPAPHYTE syrup
6850 Ft
Hepaphyte tablet promotes liver function and digestion. It is suggested in hepatopathies, sluggish liver and as a prophylactic to prevent fatty infiltration of the liver.
Hepaphyte tablet is an adjuvant to long-term antimicrobials and chemotherapy.
Data of treatment of pregnant animals are not available, no restrictions known during lactation. Side effects are unknown.
Dosage and administration: Dog: ≤ 10kg: 3 x 1,5ml; 10-20kg: 3 x 3,5ml; 20-30kg: 3 x 5ml; ≥30kg: 3 x 7-10ml; Cat: 0,5 ml/kg; Orally or mixed with feed, in the recommended dose.
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Leírás
Each 10 ml contains:
Active substances:
Extracts of:
| Phyllanthus niruri | 300 mg |
| Syrup base | Q.S. |
Other ingredients
Color: Carmoisine (EC 222-657-4)
Preservatives: Sodium-methylparaben and Sodium-propylparaben
Flavor: Blackcurrant
Lipid and glucose metabolism:
Phyllanthus niruri/amarus is also known to enhance liver function by promoting the overall health of hepatocytes and thereby improve lipid and carbohydrate metabolism.
Phenolic compounds in Phyllanthus niruri/amarus extract inhibited oxidative stress by decreasing lipid peroxidation and improving insulin signaling and beta oxidation.
Oral administration of Phyllanthus niruri/amarus extract has shown to significantly lower indicators of atherosclerosis. It prominently decreased the visceral adipose tissue, improved liver function and decreased serum levels of glucose, insulin concentrations and HOMA-IR, indicating a significant reduction in insulin resistance. Reduced serum concentrations of total cholesterol, LDL, triglycerides and MDA in animals fed with a high-fat diet. Phyllanthus niruri also suppressed FFA evoked de novo lipogenesis. It significantly reduced atherogenic ratios, ALT and theAST/ALT ratio.
Hepatic Biochemical parameters:
Significant increase in serum Alkaline Phospahatase (ALP), Alanine amino transferase (ALT), Aspartate Aminotransferase (AST), biluribin and gamma glutamyl transferase(GG) but substantially lower total protein and albumin levels were detected in animals with Thiacetamide-induced hepatotoxicity .
Treatment with Phyllanthus niruri/amarus extract could normalize these abnormal biochemical hepatic activities.
Registration number: 1705/1/NM/2020 NÉBIH ÁTI (200 ml)
- Thyagarajan SP et al: Effect of Phyllantus Amarus on Chronic Carriers of Hepatitis Virus. Lancet 1988; 8614: 764-6
- Barros ME et al: Effects of an aqueous extract from Phyllantus niruri on Calcium Oxalate crystallization in vitro. Urol Res. 2003; 30: 374-9.
- Freitas AM et al: The effect of Phyllantus Niruri on Urinary Inhibitors of Calcium Oxalate Crystallization and Other Factors Associated with Renal Stone Formation. BJU Int. 2002; 89(9): 829-34.
- Al Zarzur RH et al: Phyllantus Niruri Standardized Extract Alleviates the Progression of Non-Alcoholic Fatty Liver Disease and Decreases Risk in Sprague-Dawley Rats. Nutrients 2017; 9(7): 766-85
- Amin ZA et al: Protective Role of Phyllantus Niruri Extract Against Thioacetamide –Induced Liver Cirrhosis in Rat Model. Evidence-Based Complementary and Alternative Medicine 2012; 1-9.
Értékelések
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